My research integrates my work in complex fluids and granular media and the biomechanics of locomotion of organisms and robots to address problems in nonequilibrium systems that involve interaction of matter with complex media. For example, how do organisms like lizards, crabs, and cockroaches cope with locomotion on complex terrestrial substrates (e.g. sand, bark, leaves, and grass). I seek to discover how biological locomotion on challenging terrain results from the nonlinear, many degree of freedom interaction of the musculoskeletal and nervous systems of organisms with materials with complex physical behavior. The study of novel biological and physical interactions with complex media can lead to the discovery of principles that govern the physics of the media. My approach is to integrate laboratory and field studies of organism biomechanics with systematic laboratory studies of physics of the substrates, as well as to create mathematical and physical (robot) models of both organism and substrate. Discovery of the principles of locomotion on such materials will enhance robot agility on such substrates

Dr. Borodovsky and his group develop machine learning algorithms for computational analysis of biological sequences: DNA, RNA and proteins. Our primary focus is on prediction of protein-coding genes and regulatory sites in genomic DNA. Probabilistic models play an important role in the algorithm framework, given the probabilistic nature of biological sequence evolution.